Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study.
We studied the effect of acute tryptophan (TRP) depletion in a group of eight abstinent bulimic (BN) subjects and in 12 healthy female controls. Despite being free of episodes of binge-eating and vomiting for a prolonged period, the abstinent BN subjects still appeared to practice dietary restrain a...
| Hoofdauteurs: | , , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
1995
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| _version_ | 1826294081401126912 |
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| author | Oldman, A Walsh, A Salkovskis, P Fairburn, C Cowen, P |
| author_facet | Oldman, A Walsh, A Salkovskis, P Fairburn, C Cowen, P |
| author_sort | Oldman, A |
| collection | OXFORD |
| description | We studied the effect of acute tryptophan (TRP) depletion in a group of eight abstinent bulimic (BN) subjects and in 12 healthy female controls. Despite being free of episodes of binge-eating and vomiting for a prolonged period, the abstinent BN subjects still appeared to practice dietary restrain as judged by their food intake in a test meal. In addition, their plasma TRP concentrations were significantly lower than those of the controls. Administration of a TRP-free amino acid load (52 g) significantly lowered plasma total and free TRP. However, compared to a balanced amino acid load, this procedure did not have significant effects on mood, appetite or food intake in either the abstinent BN subjects or the healthy controls. |
| first_indexed | 2024-03-07T03:40:08Z |
| format | Journal article |
| id | oxford-uuid:bd9a4b40-4b9e-4c44-a191-3fa19afe1692 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:40:08Z |
| publishDate | 1995 |
| record_format | dspace |
| spelling | oxford-uuid:bd9a4b40-4b9e-4c44-a191-3fa19afe16922022-03-27T05:33:00ZBiochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bd9a4b40-4b9e-4c44-a191-3fa19afe1692EnglishSymplectic Elements at Oxford1995Oldman, AWalsh, ASalkovskis, PFairburn, CCowen, PWe studied the effect of acute tryptophan (TRP) depletion in a group of eight abstinent bulimic (BN) subjects and in 12 healthy female controls. Despite being free of episodes of binge-eating and vomiting for a prolonged period, the abstinent BN subjects still appeared to practice dietary restrain as judged by their food intake in a test meal. In addition, their plasma TRP concentrations were significantly lower than those of the controls. Administration of a TRP-free amino acid load (52 g) significantly lowered plasma total and free TRP. However, compared to a balanced amino acid load, this procedure did not have significant effects on mood, appetite or food intake in either the abstinent BN subjects or the healthy controls. |
| spellingShingle | Oldman, A Walsh, A Salkovskis, P Fairburn, C Cowen, P Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title | Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title_full | Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title_fullStr | Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title_full_unstemmed | Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title_short | Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study. |
| title_sort | biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects a pilot study |
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