Learning-induced plasticity in medial prefrontal cortex predicts preference malleability
Learning induces plasticity in neuronal networks. As neuronal populations contribute to multiple representations, we reasoned plasticity in one representation might influence others. We used human fMRI repetition suppression to show that plasticity induced by learning another individual's value...
| Những tác giả chính: | , , , , |
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| Định dạng: | Journal article |
| Ngôn ngữ: | English |
| Được phát hành: |
Elsevier
2015
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| _version_ | 1826294090998743040 |
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| author | Garvert, M Moutoussis, M Kurth-Nelson, Z Behrens, T Dolan, R |
| author_facet | Garvert, M Moutoussis, M Kurth-Nelson, Z Behrens, T Dolan, R |
| author_sort | Garvert, M |
| collection | OXFORD |
| description | Learning induces plasticity in neuronal networks. As neuronal populations contribute to multiple representations, we reasoned plasticity in one representation might influence others. We used human fMRI repetition suppression to show that plasticity induced by learning another individual's values impacts upon a value representation for oneself in medial prefrontal cortex (mPFC), a plasticity also evident behaviorally in a preference shift. We show this plasticity is driven by a striatal "prediction error," signaling the discrepancy between the other's choice and a subject's own preferences. Thus, our data highlight that mPFC encodes agent-independent representations of subjective value, such that prediction errors simultaneously update multiple agents' value representations. As the resulting change in representational similarity predicts interindividual differences in the malleability of subjective preferences, our findings shed mechanistic light on complex human processes such as the powerful influence of social interaction on beliefs and preferences. |
| first_indexed | 2024-03-07T03:40:17Z |
| format | Journal article |
| id | oxford-uuid:bda4f93f-a14f-4fb6-b646-db1440712787 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:40:17Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:bda4f93f-a14f-4fb6-b646-db14407127872022-03-27T05:33:24ZLearning-induced plasticity in medial prefrontal cortex predicts preference malleabilityJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bda4f93f-a14f-4fb6-b646-db1440712787EnglishSymplectic Elements at OxfordElsevier2015Garvert, MMoutoussis, MKurth-Nelson, ZBehrens, TDolan, RLearning induces plasticity in neuronal networks. As neuronal populations contribute to multiple representations, we reasoned plasticity in one representation might influence others. We used human fMRI repetition suppression to show that plasticity induced by learning another individual's values impacts upon a value representation for oneself in medial prefrontal cortex (mPFC), a plasticity also evident behaviorally in a preference shift. We show this plasticity is driven by a striatal "prediction error," signaling the discrepancy between the other's choice and a subject's own preferences. Thus, our data highlight that mPFC encodes agent-independent representations of subjective value, such that prediction errors simultaneously update multiple agents' value representations. As the resulting change in representational similarity predicts interindividual differences in the malleability of subjective preferences, our findings shed mechanistic light on complex human processes such as the powerful influence of social interaction on beliefs and preferences. |
| spellingShingle | Garvert, M Moutoussis, M Kurth-Nelson, Z Behrens, T Dolan, R Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title | Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title_full | Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title_fullStr | Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title_full_unstemmed | Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title_short | Learning-induced plasticity in medial prefrontal cortex predicts preference malleability |
| title_sort | learning induced plasticity in medial prefrontal cortex predicts preference malleability |
| work_keys_str_mv | AT garvertm learninginducedplasticityinmedialprefrontalcortexpredictspreferencemalleability AT moutoussism learninginducedplasticityinmedialprefrontalcortexpredictspreferencemalleability AT kurthnelsonz learninginducedplasticityinmedialprefrontalcortexpredictspreferencemalleability AT behrenst learninginducedplasticityinmedialprefrontalcortexpredictspreferencemalleability AT dolanr learninginducedplasticityinmedialprefrontalcortexpredictspreferencemalleability |