Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.

ग्रंथसूची विवरण
मुख्य लेखकों:	Starr, A, Sand, C, Heikal, L, Kelly, P, Spina, D, Crabtree, M, Channon, K, Leiper, J, Nandi, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2014

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
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Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
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Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
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Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
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Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
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प्रकाशित: (2005)

Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
द्वारा: Wang, W, और अन्य
प्रकाशित: (2008)

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
द्वारा: Liao, S, और अन्य
प्रकाशित: (2007)

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
द्वारा: Chen, A, और अन्य
प्रकाशित: (2005)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
द्वारा: Carnicer, R, और अन्य
प्रकाशित: (2011)

Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
द्वारा: Tie, L, और अन्य
प्रकाशित: (2009)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

GTP cyclohydrolase II structure and mechanism.
द्वारा: Ren, J, और अन्य
प्रकाशित: (2005)

Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
द्वारा: Chen, A, और अन्य
प्रकाशित: (2005)

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
द्वारा: Du, Y, और अन्य
प्रकाशित: (2008)

Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling
द्वारा: Yanan Liu, और अन्य
प्रकाशित: (2017-06-01)

Endothelial-targeted GTP cyclohydrolase I overexpression increases endothelial tetrahydrobiopterin levels and preserves eNOS coupling in eNOS overexpressing mice
द्वारा: Bendall, J, और अन्य
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Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection.
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प्रकाशित: (2010)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
द्वारा: Khoo, J, और अन्य
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303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
द्वारा: Chuaiphichai, S, और अन्य
प्रकाशित: (2014)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
द्वारा: Alp, N, और अन्य
प्रकाशित: (2003)

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
द्वारा: Carnicer, R, और अन्य
प्रकाशित: (2012)

GTP cyclohydrolase as a novel mechanism for tumour growth
द्वारा: Chen, L, और अन्य
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The protein partners of GTP cyclohydrolase I in rat organs.
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Assay for GTP Cyclohydrolase II Activity in Bacterial Extracts
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Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
द्वारा: Alp, N, और अन्य
प्रकाशित: (2004)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
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Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
द्वारा: Crabtree, M, और अन्य
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Decreased Cardiac Allograft Rejection in Mice Over-Expressing Human GTP Cyclohydrolase I.
द्वारा: Irina, I, और अन्य
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Control of GTP Cyclohydrolase I Activity during Aggregation of Dictyostelium discoideum
द्वारा: Ziegler Irmgard, और अन्य
प्रकाशित: (1995-08-01)

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
द्वारा: Vanessa A. N. Kraft, और अन्य
प्रकाशित: (2019-12-01)

Functional Studies on the Promoter Region of the Human GTP Cyclohydrolase I Gene
द्वारा: Gütlich Markus, और अन्य
प्रकाशित: (1995-08-01)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
द्वारा: Adlam, D, और अन्य
प्रकाशित: (2012)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
द्वारा: Adlam, D, और अन्य
प्रकाशित: (2012)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
द्वारा: Alp, N, और अन्य
प्रकाशित: (2003)

Increased GTP-cyclohydrolase I expression but not vitamin C treatment restored accelerated atherosclerotic lesion formation in apolipoprotein E-deficient mice overexpressing endothelial nitric oxide synthase
द्वारा: Takaya, T, और अन्य
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Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
द्वारा: Alp, N, और अन्य
प्रकाशित: (2002)

Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.

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