Human monoclonal antibodies: the residual challenge of antibody immunogenicity.

One of the major reasons for seeking human monoclonal antibodies has been to eliminate immunogenicity seen with rodent antibodies. Thus far, there has yet been no approach which absolutely abolishes that risk for cell-binding antibodies. In this short article, I draw attention to classical work whic...

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Detalles Bibliográficos
Autor Principal: Waldmann, H
Formato: Journal article
Idioma:English
Publicado: 2014