Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

As clinical evidence supports a negative impact of dysfunctional energy metabolism on the disease progression in amyotrophic lateral sclerosis, it is vital to understand how the energy metabolic pathways are altered and whether they can be restored to slow disease progression. Possible approaches in...

ver descrição completa

Detalhes bibliográficos
Principais autores: Allen, S, Hall, B, Castelli, L, Francis, L, Woof, R, Siskos, A, Kouloura, E, Gray, E, Thompson, A, Talbot, K, Higginbottom, A, Myszczynska, M, Allen, C, Stopford, M, Hemingway, J, Bauer, C, Webster, C, De Vos, K, Turner, M, Keun, H, Hautbergue, G, Ferraiuolo, L, Shaw, P
Formato: Journal article
Publicado em: Oxford University Press 2019