HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression

HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression

Cytotoxic T lymphocyte (CTL) responses against the HIV Gag protein are associated with lowering viremia; however, immune control is undermined by viral escape mutations. The rapid viral mutation rate is a key factor, but recombination may also contribute. We hypothesized that CTL responses drive the...

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Bibliographic Details
Main Authors:	Chang, C, Kist, N, Stuart Chester, T, Sreenu, V, Herman, M, Luo, M, Lunn, D, Bell, J, Plummer, F, Ball, T, Katzourakis, A, Iversen, A
Format:	Journal article
Language:	English
Published:	Nature Research 2015

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