Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis.

IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but previous findings have suggested that physical interactions with T cells may play a role. This report investi...

Полное описание

Библиографические подробности
Главные авторы: Foey, A, Green, P, Foxwell, B, Feldmann, M, Brennan, F
Формат: Journal article
Язык:English
Опубликовано: 2002