Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16.

Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16.

Enterovirus 71 (EV71) and Coxsackievirus A16 (CVA16) are the two major causative agents of hand, foot and mouth disease (HFMD), for which there are currently no licenced treatments. Here, the acquisition of resistance towards two novel capsid-binding compounds, NLD and ALD, was studied and compared...

Полное описание

Библиографические подробности
Главные авторы:	Kelly, J, De Colibus, L, Elliott, L, Fry, E, Stuart, D, Rowlands, D, Stonehouse, N
Формат:	Journal article
Язык:	English
Опубликовано:	Elsevier 2015

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