In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis.

OBJECTIVE: To detect and determine disease severity of osteoarthritis (OA) using a probe activated by matrix metalloproteinase-13 (MMP-13) in vivo in the murine destabilised medial meniscus (DMM) surgical model of OA. DESIGN: We have previously described MMP12ap and MMP13ap, internally quenched fluo...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lim, N, Meinjohanns, E, Meldal, M, Bou-Gharios, G, Nagase, H
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Elsevier 2014