Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use
Transplantation is limited by the need for life-long pharmacological immunosuppression, which carries significant morbidity and mortality. Regulatory T cell (Treg) therapy holds significant promise as a strategy to facilitate immunosuppression minimization. Polyclonal Treg therapy has been assessed...
Main Authors: | Alzhrani, A, Bottomley, M, Wood, K, Hester, J, Issa, F |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2020
|
Similar Items
-
Cytokines and peripheral tolerance to alloantigen
by: Dallman, M, et al.
Published: (1993) -
Cytokines and peripheral tolerance to alloantigen.
by: Dallman, M, et al.
Published: (1993) -
IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo.
by: Sawitzki, B, et al.
Published: (2005) -
Alloantigen-induced specific immunological unresponsiveness.
by: Wood, K, et al.
Published: (2001) -
IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells.
by: Wei, B, et al.
Published: (2010)