Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors.

Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors.

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Infarction irreversibly damages the heart, with formation of an akinetic scar that may lead to heart failure. Endogenous cardiac stem cells (CSCs) are a promising candidate cell source for restoring lost tissue and thereby preventing heart failure. CSCs may be isolated in vitro, via the formation of...

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Xehetasun bibliografikoak
Egile Nagusiak:	Tan, S, Carr, C, Yeoh, K, Schofield, C, Davies, K, Clarke, K
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2012

Antzeko izenburuak

Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors
nork: Tan, S, et al.
Argitaratua: (2011)

Preconditioning of cardiosphere-derived cells With hypoxia or prolyl-4-hydroxylase inhibitors increases stemness and decreases reliance on oxidative metabolism
nork: Tan, S, et al.
Argitaratua: (2015)

USE OF PROLYL HYDROXYLASE INHIBITORS TO INDUCE HIF-RELATED METABOLIC CHANGES AND INCREASE C-KIT EXPRESSION IN CARDIOSPHERE-DERIVED CELLS
nork: Tan, S, et al.
Argitaratua: (2011)

Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
nork: Hewitson, K, et al.
Argitaratua: (2007)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
nork: Flashman, E, et al.
Argitaratua: (2010)

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase.
nork: Mole, D, et al.
Argitaratua: (2003)

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
nork: Schlemminger, I, et al.
Argitaratua: (2003)

Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase, and is sensitive to off target inhibition by prolyl hydroxylase domain inhibitors that stabilise Hypoxia Inducible Factor
nork: Kiriakidis, S, et al.
Argitaratua: (2017)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
nork: Chan, M, et al.
Argitaratua: (2016)

2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.
nork: Mecinović, J, et al.
Argitaratua: (2009)

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
nork: Chowdhury, R, et al.
Argitaratua: (2009)

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
nork: Chowdhury, R, et al.
Argitaratua: (2013)

Studies on the substrate selectivity of the hypoxia-inducible factor prolyl hydroxylase 2 catalytic domain
nork: Abboud, M, et al.
Argitaratua: (2018)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
nork: Flashman, E, et al.
Argitaratua: (2010)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
nork: Flashman, E, et al.
Argitaratua: (2010)

Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors
nork: Holt-Martyn, J, et al.
Argitaratua: (2019)

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
nork: Tian, Y, et al.
Argitaratua: (2011)

HYPOXIC PRECONDITIONING OF CARDIOSPHERE-DERIVED CELLS TO INCREASE RETENTION IN THE INFARCTED HEART
nork: Tan, S, et al.
Argitaratua: (2010)

Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model
nork: Singh, A, et al.
Argitaratua: (2020)

Inhibition of a viral prolyl hydroxylase
nork: Langley, G, et al.
Argitaratua: (2019)

Potent and selective triazole-based inhibitors of the hypoxia-inducible factor prolyl-hydroxylases with activity in the murine brain
nork: Chan, MC, et al.
Argitaratua: (2015)

Mechanism of molecular oxygen diffusion in a hypoxia-sensing prolyl hydroxylase using multiscale simulation
nork: Domene, C, et al.
Argitaratua: (2020)

Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
nork: Lippl, K
Argitaratua: (2018)

Exploring the substrate selectivity of oxygen sensing prolyl hydroxylases
nork: Lippl, K, et al.
Argitaratua: (2015)

Molecular and Cellular Mechanisms of HIF Prolyl Hydroxylase inhibitors in Clinical Trials
nork: Yeh, TL, et al.
Argitaratua: (2017)

Prolyl hydroxylases and therapeutics.
nork: Smith, T, et al.
Argitaratua: (2010)

2-oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
nork: Abboud, M, et al.
Argitaratua: (2018)

Ethyl 2-(2,3-dihyroxybenzamido) ccetate induces hypoxia induced factor-related metabolic changes in cardiosphere-derived cells for myocardial infarction therapy
nork: Schofield, C, et al.
Argitaratua: (2016)

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.
nork: Yeoh, K, et al.
Argitaratua: (2013)

Selection of Stable Housekeeping Gene for Quantitative Real-time PCR (qRT-CR) Analysis in Human Normal and Cancerous Tissues
nork: Lasim, Masniza Muhamad
Argitaratua: (2014)

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
nork: McDonough, M, et al.
Argitaratua: (2006)

Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii
nork: Liu, T, et al.
Argitaratua: (2020)

Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding
nork: Thinnes, C, et al.
Argitaratua: (2018)

The use of dioxygen by HIF prolyl hydroxylase (PHD1).
nork: McNeill, L, et al.
Argitaratua: (2002)

Mass spectrometric studies on an oxygen sensing prolyl hydroxylase
nork: Mecinovic, J, et al.
Argitaratua: (2007)

Regulation of HIF: prolyl hydroxylases.
nork: Stolze, I, et al.
Argitaratua: (2006)

Substrate selectivity of prolyl hydroxylases
nork: McDonough, M
Argitaratua: (2018)

A fluorescent benzo[g]isoquinoline-based HIF prolyl hydroxylase inhibitor for cellular imaging
nork: Mayer, M, et al.
Argitaratua: (2018)

Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases.
nork: Lienard, B, et al.
Argitaratua: (2008)

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate.
nork: McNeill, L, et al.
Argitaratua: (2005)