Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.

Insulin resistance is characterized by excessive endothelial cell generation of potentially cytotoxic concentrations of reactive oxygen species. We examined the role of NADPH oxidase (Nox) and specifically Nox2 isoform in superoxide generation in two complementary in vivo models of human insulin res...

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Bibliographic Details
Main Authors: Sukumar, P, Viswambharan, H, Imrie, H, Cubbon, R, Yuldasheva, N, Gage, M, Galloway, S, Skromna, A, Kandavelu, P, Santos, C, Gatenby, V, Smith, J, Beech, D, Wheatcroft, S, Channon, K, Shah, A, Kearney, M
Format: Journal article
Language:English
Published: 2013

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