Associations of variants in FTO and near MC4R with obesity traits in south Asian Indians

Associations of variants in FTO and near MC4R with obesity traits in south Asian Indians

Εμφάνιση άλλων εκδόσεων (1)

Recent genome-wide association studies show that loci in FTO and melanocortin 4 receptor (MC4R) associate with obesity-related traits. Outside Western populations the associations between these variants have not always been consistent and in Indians it has been suggested that FTO relates to diabetes...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Vasan, S, Fall, T, Neville, M, Antonisamy, B, Fall, C, Geethanjali, F, Gu, H, Raghupathy, P, Samuel, P, Thomas, N, Brismar, K, Ingelsson, E, Karpe, F
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2012

Παρόμοια τεκμήρια

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ανά: Vasan, S, κ.ά.
Έκδοση: (2012)

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Έκδοση: (2014)

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ανά: Vasan, S, κ.ά.
Έκδοση: (2013)

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ανά: Vasan, S, κ.ά.
Έκδοση: (2013)

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ανά: Vasan, S, κ.ά.
Έκδοση: (2010)

Weight gain and height growth during infancy, childhood, and adolescence as predictors of adult cardiovascular risk
ανά: Antonisamy, B, κ.ά.
Έκδοση: (2016)

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ανά: Yajnik, C, κ.ά.
Έκδοση: (2009)

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ανά: A. E. Taylor, κ.ά.
Έκδοση: (2011-01-01)

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ανά: Kathryn G Ewens, κ.ά.
Έκδοση: (2011-01-01)

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ανά: Senthil K Vasan, κ.ά.
Έκδοση: (2020-04-01)

IndEcho study: Cohort study investigating birth size, childhood growth and young adult cardiovascular risk factors as predictors of midlife myocardial structure and function in South Asians
ανά: Vasan, S, κ.ά.
Έκδοση: (2018)

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ανά: Sharmili Edwin Thanarajah, κ.ά.
Έκδοση: (2023-05-01)

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ανά: Chambers, J, κ.ά.
Έκδοση: (2008)

Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk
ανά: Vasan, S, κ.ά.
Έκδοση: (2017)

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ανά: Harvest F. Gu, κ.ά.
Έκδοση: (2010-01-01)

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ανά: Barber, T, κ.ά.
Έκδοση: (2008)

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ανά: Rivas, M, κ.ά.
Έκδοση: (2013)

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ανά: Harvest F. Gu, κ.ά.
Έκδοση: (2010-04-01)

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ανά: Senthil K. Vasan, κ.ά.
Έκδοση: (2023-07-01)

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ανά: Anna Karolina Flaga, κ.ά.
Έκδοση: (2021-04-01)

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ανά: Marinou, K, κ.ά.
Έκδοση: (2014)

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ανά: Angelo Scuteri, κ.ά.
Έκδοση: (2007-07-01)

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ανά: Freathy, R, κ.ά.
Έκδοση: (2008)

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ανά: ALLAN SCHARF, κ.ά.
Έκδοση: (2023-03-01)

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ανά: Donnelly, P, κ.ά.
Έκδοση: (2016)

Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index.
ανά: Young, A, κ.ά.
Έκδοση: (2016)

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
ανά: Claussnitzer, Melina, κ.ά.
Έκδοση: (2016)

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ανά: Vasan, SK, κ.ά.
Έκδοση: (2019)

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ανά: Allayee Hooman, κ.ά.
Έκδοση: (2008-02-01)

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ανά: Kathrin Landgraf, κ.ά.
Έκδοση: (2016-01-01)

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ανά: Zeinab Naghshband, κ.ά.
Έκδοση: (2022-04-01)

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ανά: Vasan, SK, κ.ά.
Έκδοση: (2021)

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ανά: José Fernando Vila Nova de Moraes, κ.ά.
Έκδοση: (2016-07-01)

Commentary FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
ανά: Samantha eLaber, κ.ά.
Έκδοση: (2015-10-01)

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ανά: Sun, Fei, κ.ά.
Έκδοση: (2020)

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ανά: Marinou, K, κ.ά.
Έκδοση: (2014)

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ανά: M.R. Barbieri, κ.ά.
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