The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity.
Tissue inhibitors of metalloproteinases (TIMPs) are widely distributed in the animal kingdom and the human genome contains four paralogous genes encoding TIMPs 1 to 4. TIMPs were originally characterized as inhibitors of matrix metalloproteinases (MMPs), but their range of activities has now been fo...
Main Authors: | Brew, K, Nagase, H |
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Format: | Journal article |
Language: | English |
Published: |
2010
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