The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity.
Tissue inhibitors of metalloproteinases (TIMPs) are widely distributed in the animal kingdom and the human genome contains four paralogous genes encoding TIMPs 1 to 4. TIMPs were originally characterized as inhibitors of matrix metalloproteinases (MMPs), but their range of activities has now been fo...
Principais autores: | Brew, K, Nagase, H |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2010
|
Registros relacionados
-
Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors.
por: Nagase, H, et al.
Publicado em: (2003) -
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) - Physiological roles and structural basis of MMP inhibition by TIMP-1
por: Nagase, H, et al.
Publicado em: (2000) -
Protein engineering of the tissue inhibitor of metalloproteinase 1 (TIMP-1) inhibitory domain. In search of selective matrix metalloproteinase inhibitors.
por: Wei, S, et al.
Publicado em: (2003) -
Tissue inhibitors of metalloproteinases: evolution, structure and function.
por: Brew, K, et al.
Publicado em: (2000) -
Structure and function of matrix metalloproteinases and TIMPs.
por: Nagase, H, et al.
Publicado em: (2006)