Development of personalized non-invasive ventilation masks for critically ill children: a bench study
Background: Obtaining a properly fitting non-invasive ventilation (NIV) mask to treat acute respiratory failure is a major challenge, especially in young children and patients with craniofacial abnormalities. Personalization of NIV masks holds promise to improve pediatric NIV efficiency. As current...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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SpringerOpen
2024
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| _version_ | 1811139415657938944 |
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| author | Pigmans, RRWP Klein-Blommert, R van Gestel, MC Markhorst, DG Hammond, P Boomsma, P Daams, T de Jong, JMA Heeman, PM van Woensel, JBM Dijkman, CD Bem, RA |
| author_facet | Pigmans, RRWP Klein-Blommert, R van Gestel, MC Markhorst, DG Hammond, P Boomsma, P Daams, T de Jong, JMA Heeman, PM van Woensel, JBM Dijkman, CD Bem, RA |
| author_sort | Pigmans, RRWP |
| collection | OXFORD |
| description | Background: Obtaining a properly fitting non-invasive ventilation (NIV) mask to treat acute respiratory failure is a major challenge, especially in young children and patients with craniofacial abnormalities. Personalization of NIV masks holds promise to improve pediatric NIV efficiency. As current customization methods are relatively time consuming, this study aimed to test the air leak and surface pressure performance of personalized oronasal face masks using 3D printed soft materials. Personalized masks of three different biocompatible materials (silicone and photopolymer resin) were developed and tested on three head models of young children with abnormal facial features during preclinical bench simulation of pediatric NIV. Air leak percentages and facial surface pressures were measured and compared for each mask. Results: Personalized NIV masks could be successfully produced in under 12 h in a semi-automated 3D production process. During NIV simulation, overall air leak performance and applied surface pressures were acceptable, with leak percentages under 30% and average surface pressure values mostly remaining under normal capillary pressure. There was a small advantage of the masks produced with soft photopolymer resin material. Conclusion: This first, proof-of-concept bench study simulating NIV in children with abnormal facial features, showed that it is possible to obtain biocompatible, personalized oronasal masks with acceptable air leak and facial surface pressure performance using a relatively short, and semi-automated production process. Further research into the clinical value and possibilities for application of personalized NIV masks in critically ill children is needed. |
| first_indexed | 2024-09-25T04:05:44Z |
| format | Journal article |
| id | oxford-uuid:be8ec26a-5f13-4329-818b-f49b85ad1874 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:05:44Z |
| publishDate | 2024 |
| publisher | SpringerOpen |
| record_format | dspace |
| spelling | oxford-uuid:be8ec26a-5f13-4329-818b-f49b85ad18742024-05-30T09:28:29ZDevelopment of personalized non-invasive ventilation masks for critically ill children: a bench studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:be8ec26a-5f13-4329-818b-f49b85ad1874EnglishJisc Publications RouterSpringerOpen2024Pigmans, RRWPKlein-Blommert, Rvan Gestel, MCMarkhorst, DGHammond, PBoomsma, PDaams, Tde Jong, JMAHeeman, PMvan Woensel, JBMDijkman, CDBem, RABackground: Obtaining a properly fitting non-invasive ventilation (NIV) mask to treat acute respiratory failure is a major challenge, especially in young children and patients with craniofacial abnormalities. Personalization of NIV masks holds promise to improve pediatric NIV efficiency. As current customization methods are relatively time consuming, this study aimed to test the air leak and surface pressure performance of personalized oronasal face masks using 3D printed soft materials. Personalized masks of three different biocompatible materials (silicone and photopolymer resin) were developed and tested on three head models of young children with abnormal facial features during preclinical bench simulation of pediatric NIV. Air leak percentages and facial surface pressures were measured and compared for each mask. Results: Personalized NIV masks could be successfully produced in under 12 h in a semi-automated 3D production process. During NIV simulation, overall air leak performance and applied surface pressures were acceptable, with leak percentages under 30% and average surface pressure values mostly remaining under normal capillary pressure. There was a small advantage of the masks produced with soft photopolymer resin material. Conclusion: This first, proof-of-concept bench study simulating NIV in children with abnormal facial features, showed that it is possible to obtain biocompatible, personalized oronasal masks with acceptable air leak and facial surface pressure performance using a relatively short, and semi-automated production process. Further research into the clinical value and possibilities for application of personalized NIV masks in critically ill children is needed. |
| spellingShingle | Pigmans, RRWP Klein-Blommert, R van Gestel, MC Markhorst, DG Hammond, P Boomsma, P Daams, T de Jong, JMA Heeman, PM van Woensel, JBM Dijkman, CD Bem, RA Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title | Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title_full | Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title_fullStr | Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title_full_unstemmed | Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title_short | Development of personalized non-invasive ventilation masks for critically ill children: a bench study |
| title_sort | development of personalized non invasive ventilation masks for critically ill children a bench study |
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