Frequent homologous recombination deficiency in high-grade endometrial carcinomas

<p><strong>Purpose</strong> The elevated levels of somatic copy number alterations (SCNA) in a subset of high-risk endometrial cancers (EC) are suggestive of defects in pathways governing genome integrity. We sought to assess the prevalence of homologous recombination deficiency (H...

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Príomhchruthaitheoirí: Jonge, D, Auguste, A, Van Wijk, L, Schouten, P, Meijers, M, Ter Haar, N, Smit, V, Nout, R, Glaire, M, Church, D, Vrieling, H, Job, B, Boursin, Y, De Kroon, C, Rouleau, E, Leary, A, Vreeswijk, M, Bosse, T
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: American Association for Cancer Research 2018