Quantitation of minimal disease levels in chronic lymphocytic leukemia using a sensitive flow cytometric assay improves the prediction of outcome and can be used to optimize therapy.
Previous studies have suggested that the level of residual disease at the end of therapy predicts outcome in chronic lymphocytic leukemia (CLL). However, available methods for detecting CLL cells are either insensitive or not routinely applicable. A flow cytometric assay was developed that can diffe...
Main Authors: | Rawstron, A, Kennedy, B, Evans, P, Davies, F, Richards, S, Haynes, A, Russell, N, Hale, G, Morgan, G, Jack, A, Hillmen, P |
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Format: | Journal article |
Language: | English |
Published: |
2001
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