The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial

Non-communicable diseases (NCDs) place a significant burden on global health and the healthcare systems which support it. Metabolic syndrome is a major risk factor for a large number of NCDs; however, treatments remain limited. Previous research has shown the protective benefits of edible dietary sp...

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Main Authors: Al Dhaheri, AS, Alkhatib, DH, Feehan, J, Cheikh Ismail, L, Apostolopoulos, V, Stojanovska, L
Format: Journal article
Language:English
Published: MDPI 2024
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author Al Dhaheri, AS
Alkhatib, DH
Feehan, J
Cheikh Ismail, L
Apostolopoulos, V
Stojanovska, L
author_facet Al Dhaheri, AS
Alkhatib, DH
Feehan, J
Cheikh Ismail, L
Apostolopoulos, V
Stojanovska, L
author_sort Al Dhaheri, AS
collection OXFORD
description Non-communicable diseases (NCDs) place a significant burden on global health and the healthcare systems which support it. Metabolic syndrome is a major risk factor for a large number of NCDs; however, treatments remain limited. Previous research has shown the protective benefits of edible dietary spices on key components of metabolic syndrome. Therefore we performed a 12-week double-blind, placebo-controlled, randomized, clinical trial to evaluate the effect of ginger (Zingiber officinale), cinnamon (Cinnamomum), and black seed (Nigella sativa) consumption on blood glucose, lipid profiles, and body composition in 120 participants with, or at risk of, metabolic syndrome. Each participant consumed 3 g/day of powder (spice or placebo). Data related to different parameters were collected from participants at the baseline, midpoint, and endpoint of the intervention. Over the 12-week interventions, there was an improvement in a number of biochemical indices of metabolic syndrome, including fasting blood glucose, HbA1c, LCL, and total cholesterol associated with supplementation with the spices when compared to a placebo. This study provides evidence to support the adjunct use of supplementation for those at risk of metabolic syndrome and its sequelae.
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spelling oxford-uuid:bea9b106-6ee9-407f-94d5-9db84c78e45d2024-06-07T20:12:11ZThe Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled TrialJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bea9b106-6ee9-407f-94d5-9db84c78e45dEnglishJisc Publications RouterMDPI2024Al Dhaheri, ASAlkhatib, DHFeehan, JCheikh Ismail, LApostolopoulos, VStojanovska, LNon-communicable diseases (NCDs) place a significant burden on global health and the healthcare systems which support it. Metabolic syndrome is a major risk factor for a large number of NCDs; however, treatments remain limited. Previous research has shown the protective benefits of edible dietary spices on key components of metabolic syndrome. Therefore we performed a 12-week double-blind, placebo-controlled, randomized, clinical trial to evaluate the effect of ginger (Zingiber officinale), cinnamon (Cinnamomum), and black seed (Nigella sativa) consumption on blood glucose, lipid profiles, and body composition in 120 participants with, or at risk of, metabolic syndrome. Each participant consumed 3 g/day of powder (spice or placebo). Data related to different parameters were collected from participants at the baseline, midpoint, and endpoint of the intervention. Over the 12-week interventions, there was an improvement in a number of biochemical indices of metabolic syndrome, including fasting blood glucose, HbA1c, LCL, and total cholesterol associated with supplementation with the spices when compared to a placebo. This study provides evidence to support the adjunct use of supplementation for those at risk of metabolic syndrome and its sequelae.
spellingShingle Al Dhaheri, AS
Alkhatib, DH
Feehan, J
Cheikh Ismail, L
Apostolopoulos, V
Stojanovska, L
The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title_full The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title_fullStr The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title_full_unstemmed The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title_short The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial
title_sort effect of therapeutic doses of culinary spices in metabolic syndrome a randomized controlled trial
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