Structural studies of ER-associated protein quality control systems

Structural studies of ER-associated protein quality control systems

<p>ER-associated protein degradation (ERAD) is an important degradation pathway for the removal of misfolded proteins from the endoplasmic reticulum (ER). This pathway encompasses a set of evolutionary conserved mechanisms for the selection, ubiquitination and retrotranslocation of membrane an...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Robson-Tull, J
Andre forfattere:	Carvalho, P
Format:	Thesis
Sprog:	English
Udgivet:	2023
Fag:	Quality Control Cryo-EM Endoplasmic Reticulum Protein Degradation Structural Biology

Lignende værker

Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors
af: Eszter Zavodszky, et al.
Udgivet: (2019-05-01)

The Impact of Glycoengineering on the Endoplasmic Reticulum Quality Control System in Yeasts
af: Mari A. Piirainen, et al.
Udgivet: (2022-06-01)

Endoplasmic reticulum-associated degradation of glycoproteins in plants
af: Silvia eHüttner, et al.
Udgivet: (2012-04-01)

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases
af: Xiu-Yun Zhao, et al.
Udgivet: (2025-01-01)

Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins
af: Ng, Benjamin S. H., et al.
Udgivet: (2019)

Antagonistic manipulation of ER-protein quality control between biotrophic pathogenic fungi and host induced defense
af: Theoni Margaritopoulou, et al.
Udgivet: (2024-12-01)

Decreased Protein Quality Control Promotes the Cognitive Dysfunction Associated With Aging and Environmental Insults
af: Hisayo Jin, et al.
Udgivet: (2018-11-01)

AI-based quality assessment methods for protein structure models from cryo-EM
af: Han Zhu, et al.
Udgivet: (2025-06-01)

Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum
af: Hamideh Shahheydari, et al.
Udgivet: (2017-05-01)

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network
af: Songyu Wang, et al.
Udgivet: (2016-09-01)

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
af: Rachel Sharninghausen, et al.
Udgivet: (2024-11-01)

The Endoplasmic Reticulum Role in the Plant Response to Abiotic Stress
af: Sofía Reyes-Impellizzeri, et al.
Udgivet: (2021-11-01)

The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance
af: Rolf M Schmidt, et al.
Udgivet: (2019-03-01)

Circadian Oscillation Pattern of Endoplasmic Reticulum Quality Control (ERQC) Components in Human Embryonic Kidney HEK293 Cells
af: Yalcin Erzurumlu, et al.
Udgivet: (2023-04-01)

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction
af: Lan Wang, et al.
Udgivet: (2020-01-01)

The Crucial Role of Demannosylating Asparagine-Linked Glycans in ERADicating Misfolded Glycoproteins in the Endoplasmic Reticulum
af: Jianjun Zhang, et al.
Udgivet: (2021-01-01)

Label-free quantitative proteomics analysis of producer and non-producer Chinese Hamsters Ovary (CHO) cells under ER stress conditions
af: David Ryan, et al.
Udgivet: (2023-01-01)

Editorial: Post-translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease
af: Mark J. Ranek, et al.
Udgivet: (2021-08-01)

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins
af: Verena Dederer, et al.
Udgivet: (2019-06-01)

Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex
af: Patricia Franzka, et al.
Udgivet: (2023-01-01)

Structural studies of bacterial biofilm matrix fibres
af: Böhning, J
Udgivet: (2022)

Thermal-Enhanced bri1-301 Instability Reveals a Plasma Membrane Protein Quality Control System in Plants
af: Minghui Lv, et al.
Udgivet: (2018-11-01)

Chloromethylisothiazolinone induces ER stress-induced stress granule formation in human keratinocytes
af: Da-Min Jung, et al.
Udgivet: (2023-12-01)

A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM
af: Kaihua Zhang, et al.
Udgivet: (2022-12-01)

Reticulon Homology Domain-Containing Proteins and ER-Phagy
af: Manuela D’Eletto, et al.
Udgivet: (2020-02-01)

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD
af: Ginto George, et al.
Udgivet: (2020-02-01)

An optimized protocol for acquiring and processing cryo-EM data of human 26S proteasome with M1-Ub6
af: Xiang Chen, et al.
Udgivet: (2021-03-01)

Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)
af: Michael W. Martynowycz, et al.
Udgivet: (2021-09-01)

ER Morphology in the Pathogenesis of Hereditary Spastic Paraplegia
af: Sonia Sonda, et al.
Udgivet: (2021-10-01)

How to Avoid a No-Deal ER Exit
af: Tiziana Anelli, et al.
Udgivet: (2019-09-01)

ER Stress-Sensor Proteins and ER-Mitochondrial Crosstalk—Signaling Beyond (ER) Stress Response
af: Vaishali Kumar, et al.
Udgivet: (2021-01-01)

Compartmentalization and Trafficking in Endoplasmic Reticulum Protein Quality Control
af: Gerardo Z. Lederkremer
Udgivet: (2023-03-01)

From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery
af: Agirrezabala Xabier, et al.
Udgivet: (2010-04-01)

Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells
af: Guimei Yu, et al.
Udgivet: (2022-06-01)

Structural basis for pharmacological modulation of the TRPC6 channel
af: Yonghong Bai, et al.
Udgivet: (2020-03-01)

Endoplasmic Reticulum-Mediated Protein Quality Control in Arabidopsis
af: Jianming eLi, et al.
Udgivet: (2014-04-01)

The divergent ER-mitochondria encounter structures (ERMES) are conserved in parabasalids but lost in several anaerobic lineages with hydrogenosomes
af: Jitka Kučerová, et al.
Udgivet: (2023-11-01)

The promoter of filamentation (POF1) protein from <it>Saccharomyces cerevisiae </it>is an ATPase involved in the protein quality control process
af: Costa Iris M, et al.
Udgivet: (2011-12-01)

Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner
af: Wei Shao (邵威), et al.
Udgivet: (2016-08-01)

Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes
af: Mark P. Jedrychowski, et al.
Udgivet: (2015-11-01)