Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes.

BACKGROUND: The identification of filaggrin mutations has contributed towards our understanding of hereditary factors associated with epidermal dysfunction observed in individuals with atopic eczema (AE). However, factors that predispose to acquired filaggrin modulation are not well understood. Inte...

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Những tác giả chính: Gutowska-Owsiak, D, Schaupp, A, Salimi, M, Taylor, S, Ogg, G
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2011