$Functional characterization of a GGPPS variant identified in atypical femoral fracture patients and delineation of the role of GGPPS in bone-relevant cell types$

Functional characterization of a GGPPS variant identified in atypical femoral fracture patients and delineation of the role of GGPPS in bone-relevant cell types

Atypical femoral fractures (AFFs) are a rare but potentially devastating event, often but not always linked to bisphosphonate (BP) therapy. The pathogenic mechanisms underlying AFFs remain obscure, and there are no tests available that might assist in identifying those at high risk of AFF. We previo...

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Hlavní autoři:	Roca-Ayats, N, Ng, P, Garcia-Giralt, N, Falcó-Mascaró, M, Cozar, M, Abril, J, Quesada Gómez, J, Prieto-Alhambra, D, Nogués, X, Dunford, J, Russell, R, Baron, R, Grinberg, D, Balcells, S, Díez-Pérez, A
Médium:	Journal article
Jazyk:	English
Vydáno:	Wiley 2018

Functional characterization of a GGPPS variant identified in atypical femoral fracture patients and delineation of the role of GGPPS in bone-relevant cell types

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