Association between - 308 tumour necrosis factor promoter polymorphism and bronchial hyperreactivity in asthma.

BACKGROUND: Tumour necrosis factor (TNF) is a pivotal cytokine in the inflammation underlying asthma. The TNF gene is located in the polymorphic HLA class 3 region on chromosome 6p. Several polymorphisms in this region have been described and associated with alteration of TNF secretion in vitro. OB...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Li Kam Wa, T, Mansur, A, Britton, J, Williams, G, Pavord, I, Richards, K, Campbell, D, Morton, N, Holgate, S, Morrison, J
Materialtyp: Journal article
Språk:English
Publicerad: 1999