CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

The ligand for CD40 (CD40L) is expressed on the surface of activated CD4+ T cells and its role in T-B cell collaborations and thymus-dependent humoral immunity is well established. Recently, by generating CD40L-knockout mice, we have confirmed its previously described role in humoral immunity and de...

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Bibliographic Details
Main Authors:	Borrow, P, Tishon, A, Lee, S, Xu, J, Grewal, I, Oldstone, M, Flavell, R
Format:	Journal article
Language:	English
Published:	1996

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