Activation of Notch signaling in human colon adenocarcinoma.

Notch and Wnt signaling function together to regulate colonic progenitor cell division and differentiation. Studies in mice have also shown that Notch signaling is required for adenoma formation in response to elevated Wnt-pathway signaling that occurs in the APCMin mouse model of human adenomatous...

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Main Authors: Reedijk, M, Odorcic, S, Zhang, H, Chetty, R, Tennert, C, Dickson, B, Lockwood, G, Gallinger, S, Egan, SE
格式: Journal article
语言:English
出版: 2008