Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis.

BACKGROUND: Several studies have suggested that microsatellite instability (MSI) resulting from defective DNA mismatch repair confers a better prognosis in colorectal cancer (CRC). Recently, however, data have suggested this is secondary to the effects of ploidy/chromosomal instability (CIN). To es...

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Main Authors: Walther, A, Houlston, R, Tomlinson, I
פורמט: Journal article
שפה:English
יצא לאור: 2008