Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.

We propose a method for the reconstruction of volumetric fetal MRI from 2D slices, comprising super-resolution reconstruction of the volume interleaved with slice-to-volume registration to correct for the motion. The method incorporates novel intensity matching of acquired 2D slices and robust stati...

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Main Authors: Kuklisova-Murgasova, M, Quaghebeur, G, Rutherford, M, Hajnal, J, Schnabel, J
Format: Journal article
Language:English
Published: 2012
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author Kuklisova-Murgasova, M
Quaghebeur, G
Rutherford, M
Hajnal, J
Schnabel, J
author_facet Kuklisova-Murgasova, M
Quaghebeur, G
Rutherford, M
Hajnal, J
Schnabel, J
author_sort Kuklisova-Murgasova, M
collection OXFORD
description We propose a method for the reconstruction of volumetric fetal MRI from 2D slices, comprising super-resolution reconstruction of the volume interleaved with slice-to-volume registration to correct for the motion. The method incorporates novel intensity matching of acquired 2D slices and robust statistics which completely excludes identified misregistered or corrupted voxels and slices. The reconstruction method is applied to motion-corrupted data simulated from MRI of a preterm neonate, as well as 10 clinically acquired thick-slice fetal MRI scans and three scan-sequence optimized thin-slice fetal datasets. The proposed method produced high quality reconstruction results from all the datasets to which it was applied. Quantitative analysis performed on simulated and clinical data shows that both intensity matching and robust statistics result in statistically significant improvement of super-resolution reconstruction. The proposed novel EM-based robust statistics also improves the reconstruction when compared to previously proposed Huber robust statistics. The best results are obtained when thin-slice data and the correct approximation of the point spread function is used. This paper addresses the need for a comprehensive reconstruction algorithm of 3D fetal MRI, so far lacking in the scientific literature.
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spelling oxford-uuid:bf236e14-3cf3-4716-bc84-a251fafc18ac2022-03-27T05:45:10ZReconstruction of fetal brain MRI with intensity matching and complete outlier removal.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:bf236e14-3cf3-4716-bc84-a251fafc18acEnglishSymplectic Elements at Oxford2012Kuklisova-Murgasova, MQuaghebeur, GRutherford, MHajnal, JSchnabel, JWe propose a method for the reconstruction of volumetric fetal MRI from 2D slices, comprising super-resolution reconstruction of the volume interleaved with slice-to-volume registration to correct for the motion. The method incorporates novel intensity matching of acquired 2D slices and robust statistics which completely excludes identified misregistered or corrupted voxels and slices. The reconstruction method is applied to motion-corrupted data simulated from MRI of a preterm neonate, as well as 10 clinically acquired thick-slice fetal MRI scans and three scan-sequence optimized thin-slice fetal datasets. The proposed method produced high quality reconstruction results from all the datasets to which it was applied. Quantitative analysis performed on simulated and clinical data shows that both intensity matching and robust statistics result in statistically significant improvement of super-resolution reconstruction. The proposed novel EM-based robust statistics also improves the reconstruction when compared to previously proposed Huber robust statistics. The best results are obtained when thin-slice data and the correct approximation of the point spread function is used. This paper addresses the need for a comprehensive reconstruction algorithm of 3D fetal MRI, so far lacking in the scientific literature.
spellingShingle Kuklisova-Murgasova, M
Quaghebeur, G
Rutherford, M
Hajnal, J
Schnabel, J
Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title_full Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title_fullStr Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title_full_unstemmed Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title_short Reconstruction of fetal brain MRI with intensity matching and complete outlier removal.
title_sort reconstruction of fetal brain mri with intensity matching and complete outlier removal
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AT rutherfordm reconstructionoffetalbrainmriwithintensitymatchingandcompleteoutlierremoval
AT hajnalj reconstructionoffetalbrainmriwithintensitymatchingandcompleteoutlierremoval
AT schnabelj reconstructionoffetalbrainmriwithintensitymatchingandcompleteoutlierremoval