Two-pore channels for integrative Ca signaling.

Two-pore channels (TPCs) are related to voltage-gated Ca(2+) and Na(+) channels. They most likely work as dimers with each of the two TPC protein subunits containing two pore-forming domains. Recent studies suggest that TPCs are expressed on the membranes of endosomes and lysosomes where they form r...

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Autors principals: Zhu, M, Evans, A, Ma, J, Parrington, J, Galione, A
Format: Journal article
Idioma:English
Publicat: 2010