The mutation rate and cancer.
The selection of advantageous mutations underlies tumorigenesis. The growth of a tumor is therefore a form of evolution at the somatic level, in which the population is comprised of individual cells within the tumor. Models of tumorigenesis have considered the relative importance of mutation and sel...
Main Authors: | Tomlinson, I, Novelli, MR, Bodmer, W |
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Format: | Journal article |
Language: | English |
Published: |
1996
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