Enantioselective suzuki reactions: catalytic asymmetric synthesis of compounds containing quaternary carbon centers.
Prochiral ditriflates can act as substrates in asymmetric Suzuki couplings by using an enantioselective desymmetrization strategy. The products are obtained with selectivities up to 86% ee and contain a quaternary carbon center and a synthetically useful vinyl triflate functionality (see scheme).
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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