Harnessing invariant NKT-cells to enhance antigen specific immune responses

Harnessing invariant NKT-cells to enhance antigen specific immune responses

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Cerundolo, V
Formáid:	Journal article
Foilsithe / Cruthaithe:	2014

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B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.
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The location of splenic NKT cells favours their rapid activation by blood-borne antigen.
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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.
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Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
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