Diabetes reduces vascular tetrahydrobiopterin levels by oxidation: Insights from a GTPCH-transgenic mouse model

Geahča maid

• Increased endothelial tetrahydrobiopterin levels in GTPCH-transgenic mice
  Dahkki: Alp, N, et al.
  Almmustuhtton: (2002)
• Increased endothelial tetrahydrobiopterin levels by GTPCH over expression in transgenic mice prevents diabetic endothelial dysfunction
  Dahkki: Alp, N, et al.
  Almmustuhtton: (2003)
• Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation
  Dahkki: Cai, S, et al.
  Almmustuhtton: (2004)
• Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
  Dahkki: Alp, N, et al.
  Almmustuhtton: (2003)
• Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
  Dahkki: Alp, N, et al.
  Almmustuhtton: (2003)