Diabetes reduces vascular tetrahydrobiopterin levels by oxidation: Insights from a GTPCH-transgenic mouse model

Diabetes reduces vascular tetrahydrobiopterin levels by oxidation: Insights from a GTPCH-transgenic mouse model

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Alp, N, Mussa, S, Goh, N, Cai, S, Channon, K
Μορφή:	Conference item
Έκδοση:	2003

Παρόμοια τεκμήρια

Increased endothelial tetrahydrobiopterin levels in GTPCH-transgenic mice
ανά: Alp, N, κ.ά.
Έκδοση: (2002)

Increased endothelial tetrahydrobiopterin levels by GTPCH over expression in transgenic mice prevents diabetic endothelial dysfunction
ανά: Alp, N, κ.ά.
Έκδοση: (2003)

Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation
ανά: Cai, S, κ.ά.
Έκδοση: (2004)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
ανά: Alp, N, κ.ά.
Έκδοση: (2003)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
ανά: Alp, N, κ.ά.
Έκδοση: (2003)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
ανά: Alp, N, κ.ά.
Έκδοση: (2003)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
ανά: Alp, N, κ.ά.
Έκδοση: (2004)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
ανά: Alp, N, κ.ά.
Έκδοση: (2004)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
ανά: Cai, S, κ.ά.
Έκδοση: (2005)

Endothelial tetrahydrobiopterin regulates eNOS coupling/uncoupling independent of vascular disease: Insights from targeted transgenic models
ανά: Bendall, J, κ.ά.
Έκδοση: (2004)

huGTPCH Expressing S plus S-Antilles Mice Have Reduced Gardos Channel Activity, Endothelin-1 Expression, and Endothelin Receptor A and B Expression, While Total Biopterin and Percent Tetrahydrobiopterin Are Increased
ανά: Romero, JR, κ.ά.
Έκδοση: (2008)

The % tetrahydrobiopterin (BH4) and serine 1177 phosphorylation 19 reduced in sickle transgenic mice
ανά: Chen, Q, κ.ά.
Έκδοση: (2007)

GTPCH I overexpression decreases atherosclerotic lesion formation in apolipoprotein E-deficient/eNOS transgenic mice
ανά: Takaya, T, κ.ά.
Έκδοση: (2004)

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
ανά: Channon, K
Έκδοση: (2004)

Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular inflammation in apolipoprotein E-knockout mice.
ανά: Schmidt, T, κ.ά.
Έκδοση: (2010)

Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.
ανά: Khoo, J, κ.ά.
Έκδοση: (2004)

Tetrahydrobiopterin (BH4) Improves Endothelial Cell Survival After Vascular Injury
ανά: Rinze, R, κ.ά.
Έκδοση: (2008)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
ανά: Alp, N, κ.ά.
Έκδοση: (2004)

Increased endothelial tetrahydrobiopterin reduces in stent stenosis in apolipoprotein E-knockout mice
ανά: Ali, Z, κ.ά.
Έκδοση: (2007)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
ανά: Alp, N, κ.ά.
Έκδοση: (2003)

Correction of tetrahydrobiopterin deficiency - Implications for dopa responsive dystonia and other inherited disorders of tetrahydrobiopterin metabolism
ανά: Heales, S, κ.ά.
Έκδοση: (2005)

The relative contributions of cardiomyocytes versus endothelial cells to cardiac BH4 production; studies in novel cardiomyocyte- and endothelial-specific GTPCH I-deficient mice
ανά: Bendall, J, κ.ά.
Έκδοση: (2012)

Increased Endothelial Tetrahydrobiopterin Reduces In Stent Stenosis in Apolipoprotein E-Knockout Mice
ανά: Ali, Z, κ.ά.
Έκδοση: (2011)

Regulation of eNOS function by tetrahydrobiopterin in vascular disease
ανά: Channon, K
Έκδοση: (2004)

Prevention of hypoxia-induced pulmonary hypertension and vascular remodelling by targeting endothelial tetrahydrobiopterin-dependent nitric oxide synthase regulation
ανά: Khoo, J, κ.ά.
Έκδοση: (2005)

Tetrahydrobiopterin deficiency increases susceptibility to atherosclerosis
ανά: Khoo, J, κ.ά.
Έκδοση: (2005)

Tetrahydrobiopterin and nitric oxide synthase recouplers
ανά: Channon, KM
Έκδοση: (2020)

Dihydrofolate reductase is required to maintain endothelial nitric oxide synthase coupling in vivo: Insights from methotrexate-treated BH4 deficient and GTPCH overexpressing mice
ανά: Crabtree, M, κ.ά.
Έκδοση: (2010)

Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling
ανά: Khoo, J, κ.ά.
Έκδοση: (2005)

Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.
ανά: Crabtree, M, κ.ά.
Έκδοση: (2011)

Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease
ανά: Crabtree, M, κ.ά.
Έκδοση: (2011)

Tetrahydrobiopterin: a vascular redox target to improve endothelial function.
ανά: Channon, K
Έκδοση: (2012)

Increased endothelial tetrahydrobiopterin synthesis reduces vein graft atherosclerosis in ApoE-knockout mice
ανά: Ali, Z, κ.ά.
Έκδοση: (2005)

Low-dose Tetrahydrobiopterin Supplementation Reduces Atherosclerosis Progression in Apolipoprotein E-Knockout Mice via Effects on Vascular T cell Infiltration
ανά: Schmidt, T, κ.ά.
Έκδοση: (2009)

Tetrahydrobiopterin deficiency uncouples nitric oxide synthase and causes pulmonary hypertension
ανά: Khoo, J, κ.ά.
Έκδοση: (2004)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
ανά: Bendall, J, κ.ά.
Έκδοση: (2005)

Tetrahydrobiopterin regulates vagal control of heart rate
ανά: Adlam, D, κ.ά.
Έκδοση: (2005)

Tetrahydrobiopterin deficiency causes pulmonary hypertension: Effects on lung superoxide levels, hypoxic pulmonary vasoconstriction and vascular remodelling
ανά: Khoo, J, κ.ά.
Έκδοση: (2004)

Tetrahydrobiopterin in the vascular system
ανά: Walter Roland, κ.ά.
Έκδοση: (2001-08-01)

Tetrahydrobiopterin: coupling nitric oxide and redox signalling in cardiovascular disease
ανά: Channon, K
Έκδοση: (2012)