Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.

New anti-tubercular drugs and drug targets are urgently needed to reduce the time for treatment and also to identify agents that will be effective against Mycobacterium tuberculosis persisting intracellularly. Mycobacteria have a unique cell wall. Deletion of the gene for arylamine N-acetyltransfera...

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Autori principali: Westwood, I, Bhakta, S, Russell, A, Fullam, E, Anderton, M, Kawamura, A, Mulvaney, A, Vickers, R, Bhowruth, V, Besra, G, Lalvani, A, Davies, S, Sim, E
Natura: Journal article
Lingua:English
Pubblicazione: Higher Education Press 2010