Mutagenesis of the human IgA1 heavy chain tailpiece that prevents dimer assembly.
The structural features of the human IgA1 tailpiece required for interaction with J chain in IgA dimer assembly were investigated using a protein engineering approach. Wild-type and mutant forms of IgA1 were expressed in the mouse myeloma cell line, J558L, which endogenously expresses J chain. Wild-...
প্রধান লেখক: | Atkin, J, Pleass, R, Owens, R, Woof, J |
---|---|
বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1996
|
অনুরূপ উপাদানগুলি
-
Purification and characterization of chimeric human IgA1 and IgA2 expressed in COS and Chinese hamster ovary cells.
অনুযায়ী: Morton, H, অন্যান্য
প্রকাশিত: (1993) -
Development of a human IgA antibody specific for the tumor antigen TAG-72
অনুযায়ী: Ingram, P, অন্যান্য
প্রকাশিত: (1996) -
Development of a human IgA antibody specific for the tumour antigen TAG-72.
অনুযায়ী: Ingram, P, অন্যান্য
প্রকাশিত: (1997) -
Dimeric and polymeric IgA, but not monomeric IgA, enhance the production of IL-6 by human renal mesangial cells
অনুযায়ী: T. J. F. Reterink, অন্যান্য
প্রকাশিত: (1996-01-01) -
Neuraminidase treatment abrogates the binding abnormality of IgA1 from IgA nephropathy patients and the differential charge distribution of its alpha-heavy chains
অনুযায়ী: Hashim, Onn Haji, অন্যান্য
প্রকাশিত: (2001)