Mutagenesis of the human IgA1 heavy chain tailpiece that prevents dimer assembly.

The structural features of the human IgA1 tailpiece required for interaction with J chain in IgA dimer assembly were investigated using a protein engineering approach. Wild-type and mutant forms of IgA1 were expressed in the mouse myeloma cell line, J558L, which endogenously expresses J chain. Wild-...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Atkin, J, Pleass, R, Owens, R, Woof, J
स्वरूप: Journal article
भाषा:English
प्रकाशित: 1996

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