Mutagenesis of the human IgA1 heavy chain tailpiece that prevents dimer assembly.

The structural features of the human IgA1 tailpiece required for interaction with J chain in IgA dimer assembly were investigated using a protein engineering approach. Wild-type and mutant forms of IgA1 were expressed in the mouse myeloma cell line, J558L, which endogenously expresses J chain. Wild-...

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Detaylı Bibliyografya
Asıl Yazarlar: Atkin, J, Pleass, R, Owens, R, Woof, J
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 1996

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