Templated interlocked host structures for the recognition and sensing of charged substrates
<p>This thesis describes the synthesis of acyclic, macrocyclic and, in particular, interlocked anion and ion-pair receptors and sensors.</p> <p><strong>Chapter One</strong> will introduce the field of supramolecular chemistry with particular emphasis on areas which are...
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| Format: | Thesis |
| Language: | English |
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2014
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| _version_ | 1797109875492257792 |
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| author | Knighton, RC |
| author2 | Beer, P |
| author_facet | Beer, P Knighton, RC |
| author_sort | Knighton, RC |
| collection | OXFORD |
| description | <p>This thesis describes the synthesis of acyclic, macrocyclic and, in particular, interlocked anion and ion-pair receptors and sensors.</p> <p><strong>Chapter One</strong> will introduce the field of supramolecular chemistry with particular emphasis on areas which are pertinent to this thesis, including anion receptor design and templated synthesis of interlocked structures.</p> <p><strong>Chapter Two</strong> focuses on the synthesis of new heteroditopic macrocycles functionalised with both cation and anion recognition sites and their incorporation into interlocked architectures. The affinity for a range of anions and ion-pairs is explored <em>via</em> <sup>1</sup>H NMR and UV-visible spectroscopy as well as by X-ray crystallography.</p> <p><strong>Chapter Three</strong> details the incorporation of <em>d</em>- and <em>f</em>-metal luminescent reporter groups into an isophthalamide motif in order to construct acyclic, macrocyclic and [2]rotaxane receptors.</p> <p><strong>Chapter Four</strong> investigates the synthesis of complex higher-order interlocked structures through post-synthetic modification of lower-order interlocked structures.</p> <p><strong>Chapter Five</strong> explores the potential for fluorescent gold nanoparticle conjugates to act as luminescent and colourimetric sensors for chemical warfare agents (CWAs) by employing a fluorescent displacement assay technique.</p> |
| first_indexed | 2024-03-07T07:47:27Z |
| format | Thesis |
| id | oxford-uuid:bf8189fa-4409-483b-a3b8-789f0d62c81c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:47:27Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:bf8189fa-4409-483b-a3b8-789f0d62c81c2023-06-13T16:23:44ZTemplated interlocked host structures for the recognition and sensing of charged substratesThesishttp://purl.org/coar/resource_type/c_db06uuid:bf8189fa-4409-483b-a3b8-789f0d62c81cSupramolecular chemistryEnglishOxford University Research Archive - Valet2014Knighton, RCBeer, P<p>This thesis describes the synthesis of acyclic, macrocyclic and, in particular, interlocked anion and ion-pair receptors and sensors.</p> <p><strong>Chapter One</strong> will introduce the field of supramolecular chemistry with particular emphasis on areas which are pertinent to this thesis, including anion receptor design and templated synthesis of interlocked structures.</p> <p><strong>Chapter Two</strong> focuses on the synthesis of new heteroditopic macrocycles functionalised with both cation and anion recognition sites and their incorporation into interlocked architectures. The affinity for a range of anions and ion-pairs is explored <em>via</em> <sup>1</sup>H NMR and UV-visible spectroscopy as well as by X-ray crystallography.</p> <p><strong>Chapter Three</strong> details the incorporation of <em>d</em>- and <em>f</em>-metal luminescent reporter groups into an isophthalamide motif in order to construct acyclic, macrocyclic and [2]rotaxane receptors.</p> <p><strong>Chapter Four</strong> investigates the synthesis of complex higher-order interlocked structures through post-synthetic modification of lower-order interlocked structures.</p> <p><strong>Chapter Five</strong> explores the potential for fluorescent gold nanoparticle conjugates to act as luminescent and colourimetric sensors for chemical warfare agents (CWAs) by employing a fluorescent displacement assay technique.</p> |
| spellingShingle | Supramolecular chemistry Knighton, RC Templated interlocked host structures for the recognition and sensing of charged substrates |
| title | Templated interlocked host structures for the recognition and sensing of charged substrates |
| title_full | Templated interlocked host structures for the recognition and sensing of charged substrates |
| title_fullStr | Templated interlocked host structures for the recognition and sensing of charged substrates |
| title_full_unstemmed | Templated interlocked host structures for the recognition and sensing of charged substrates |
| title_short | Templated interlocked host structures for the recognition and sensing of charged substrates |
| title_sort | templated interlocked host structures for the recognition and sensing of charged substrates |
| topic | Supramolecular chemistry |
| work_keys_str_mv | AT knightonrc templatedinterlockedhoststructuresfortherecognitionandsensingofchargedsubstrates |