Differential gene expression in macrophages from human atherosclerotic plaques shows convergence on pathways implicated by genome-wide association study risk variants
<h4>Objective</h4> <p>Plaque macrophages are intricately involved in atherogenesis and plaque destabilization. We sought to identify functional pathways in human plaque macrophages that are differentially regulated in respect of (1) plaque stability and (2) lipid content. We hypot...
Main Authors: | Chai, J, Ruparelia, N, Goel, A, Kyriakou, T, Biasiolli, L, Edgar, L, Handa, A, Farrall, M, Watkins, H, Choudhury, R |
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Format: | Journal article |
Published: |
American Heart Association
2018
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