"Target trial emulation" for observational studies - potential and pitfalls

"Target trial emulation" for observational studies - potential and pitfalls

To improve the quality of observational studies, target trial emulation requires careful specification of design elements, analytic methods for addressing confounding, and reporting of sensitivity analyses.

Bibliographic Details
Main Authors:	Hubbard, RA, Gatsonis, CA, Hogan, JW, Hunter, DJ, Normand, S-LT, Troxel, AB
Format:	Journal article
Language:	English
Published:	Massachusetts Medical Society 2024

Similar Items

Kony 2012 : potentials and pitfalls of social media
by: Ng, Joel
Published: (2012)

Effect of immediate initiation of invasive ventilation on mortality in acute hypoxemic respiratory failure: a target trial emulation
by: Mellado-Artigas, Ricard, et al.
Published: (2024)

Association between a selective 5-HT4 receptor agonist and incidence of major depressive disorder: emulated target trial
by: de Cates, AN, et al.
Published: (2024)

The Indonesian defence forces and disaster relief : potential pitfalls and challenges
by: Evan A. Laksmana
Published: (2011)

Emulating an atomic gyroscope with multiple accelerometers
by: Shettell, Nathan, et al.
Published: (2024)

Partnering with AI for instrument development: possibilities and pitfalls
by: Beghetto, Ronald A., et al.
Published: (2025)

Adsorption Kinetics Emulation With Lattice Gas Cellular Automata
by: Sun, Baichuan, et al.
Published: (2017)

SoK: Understanding Design Choices and Pitfalls of Trusted Execution Environments
by: Li, Mengyuan, et al.
Published: (2024)

UMP associates need to emulate leadership of Prophet Muhammad SAW in management of organisation
by: Nor Salwana, Mohammad Idris
Published: (2023)

Possibilities and pitfalls? Moderate drinking and alcohol abstinence at home since the COVID-19 lockdown
by: Nicholls, Emily, et al.
Published: (2021)

SongGen: Framework for Controllable AI Song Generation through Interactive Songwriting and Artist Emulation
by: Arora, Ajay
Published: (2024)

Targeting the youth : the potentials of the traditional Chinese medicine industry in Singapore.
by: Long, Li Yann., et al.
Published: (2008)

Novel statistical emulator construction for volcanic ash transport model Ash3d with physically motivated measures
by: Yang, Qingyuan, et al.
Published: (2022)

Targeting NAPE-PLD: assessing its potential in the fight against malaria
by: Goh, Xiu Ling
Published: (2024)

The potential of smartphone apps in informing protobacco and antitobacco messaging efforts among underserved communities : longitudinal observational study
by: Lee, Edmund Wei Jian, et al.
Published: (2021)

Determining targets for antiretroviral drug concentrations: a causal framework illustrated with pediatric efavirenz data from the CHAPAS-3 trial
by: Schomaker, M, et al.
Published: (2024)

Slip rate deficit and earthquake potential on shallow megathrusts
by: Lindsey, Eric Ostrom, et al.
Published: (2022)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
by: O'Brien, EM
Published: (2012)

Resistant hypertension and mortality: an observational cohort study
by: de la Sierra, A, et al.
Published: (2024)

UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract
by: Stritt, Kevin, et al.
Published: (2024)

CIDP trials and tribulations
by: Rinaldi, S
Published: (2024)

The study of target costing in Singapore.
by: Chia Wei Siang, Goh Sze Hwee, Tea Wei Li
Published: (2014)

Comprehensive insights into Sitobion avenae preferences and performance on Pakistan’s wheat cultivars leading to identification of potential RNAi targets
by: Mukhtar, Ruhma, et al.
Published: (2024)

In silico investigations and potential approaches of Tectona grandis via targeting MMP-9 for triple negative breast cancer
by: Permana, Sofy, et al.
Published: (2024)

Unveiling potential therapeutic targets for breast cancer recurrence: differentially expressed genes and pathways in post-surgery patients
by: Hamad, Hamad Ali, et al.
Published: (2024)

A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system
by: Shen, Yunbing, et al.
Published: (2021)

Microtremor observations in Kallang area
by: Chong, Lit Yung.
Published: (2009)

Data for the ‘Orchid Observers’ project
by: Shuttleworth, S, et al.
Published: (2017)

Collaborative model of care between Orthopaedics and allied healthcare professionals in knee osteoarthritis (CONNACT) : study protocol for an effectiveness-implementation hybrid randomized control trial
by: Tan, Bryan Yijia, et al.
Published: (2021)

Very small effects of an imagery-based randomised trial to promote adherence to wearing face coverings during the COVID-19 pandemic and identification of future intervention targets
by: Conroy, Dom, et al.
Published: (2022)

Observation of an acoustic octupole topological insulator
by: Xue, Haoran, et al.
Published: (2021)

GWTC-3: Compact Binary Coalescences Observed by LIGO and Virgo during the Second Part of the Third Observing Run
by: Sudhir, Vivishek
Published: (2024)

Nasalization in Lhasa Tibetan
by: Hogan, Lee C.
Published: (2024)

When a test is more than just a test: findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial)
by: Brown, S, et al.
Published: (2024)

Evaluating the impact of the biofire filmarray in childhood meningitis: an Observational Cohort Study
by: Kadambari, S, et al.
Published: (2024)

Instrumenting Observability in a Decentralized Microservice Architecture
by: Liu, Helen X.
Published: (2024)

Defining proteoform-specific interactions for drug targeting in a native cell signalling environment
by: Lutomski, CA, et al.
Published: (2025)

MPEG-4 system development and trial investigation
by: Yu, Jun.
Published: (2008)

Protocol and statistical analysis plan for the TREATT trial
by: Estcourt, L, et al.
Published: (2024)

Soft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from the European Society of Musculoskeletal Radiology (ESSR)
by: Noebauer-Huhmann, I, et al.
Published: (2024)