Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
<p><strong>Background</strong> Despite their revolutionary success in cancer treatment over the last decades, immunotherapies encounter limitations in certain tumor types and patients. The efficacy of immunotherapies depends on tumor antigen-specific CD8 T-cell viability and functi...
Κύριοι συγγραφείς: | Finisguerra, V, Dvorakova, T, Formenti, M, Van Meerbeeck, P, Mignion, L, Gallez, B, Van den Eynde, BJ |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
BMJ Publishing Group
2023
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
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Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
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Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
ανά: Zhu, J, κ.ά.
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Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
ανά: Tereza Dvorakova, κ.ά.
Έκδοση: (2024-09-01) -
Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism
ανά: Zhu, J, κ.ά.
Έκδοση: (2018)