Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.

Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.

UNLABELLED: (11)C-Pittsburgh compound B (PiB) marks Abeta amyloidosis, a key pathogenetic process in Alzheimer disease (AD). The use of (11)C-PiB is limited to centers with a cyclotron. Development of the (18)F-labeled thioflavin derivative of PiB, (18)F-flutemetamol, could hugely increase the avail...

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Bibliografiska uppgifter
Huvudupphovsmän:	Nelissen, N, Van Laere, K, Thurfjell, L, Owenius, R, Vandenbulcke, M, Koole, M, Bormans, G, Brooks, D, Vandenberghe, R
Materialtyp:	Journal article
Språk:	English
Publicerad:	2009

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