Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.

UNLABELLED: (11)C-Pittsburgh compound B (PiB) marks Abeta amyloidosis, a key pathogenetic process in Alzheimer disease (AD). The use of (11)C-PiB is limited to centers with a cyclotron. Development of the (18)F-labeled thioflavin derivative of PiB, (18)F-flutemetamol, could hugely increase the avail...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Nelissen, N, Van Laere, K, Thurfjell, L, Owenius, R, Vandenbulcke, M, Koole, M, Bormans, G, Brooks, D, Vandenberghe, R
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2009