Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer.

Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer.

Activation of mitogen/extracellular-signal-regulated kinase kinase 5/extracellular signal-regulated kinase-5 (MEK5/ERK5) growth signalling is coupled to increased cell proliferation in prostate cancer (PCa). Dysregulation of the DNA replication licensing pathway, a critical step in growth control do...

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Bibliographic Details
Main Authors:	Dudderidge, T, McCracken, SR, Loddo, M, Fanshawe, T, Kelly, J, Neal, D, Leung, H, Williams, G, Stoeber, K
Format:	Journal article
Language:	English
Published:	2007

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