S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models.

RATIONALE: Serotonin (5-HT)(2C) receptors are implicated in the control of mood, and their blockade is of potential interest for the management of anxiodepressive states. OBJECTIVES: Herein, we characterized the in vitro and in vivo pharmacological profile of the novel benzourea derivative, S32006....

Полное описание

Библиографические подробности
Главные авторы: Dekeyne, A, Mannoury la Cour, C, Gobert, A, Brocco, M, Lejeune, F, Serres, F, Sharp, T, Daszuta, A, Soumier, A, Papp, M, Rivet, J, Flik, G, Cremers, T, Muller, O, Lavielle, G, Millan, M
Формат: Journal article
Язык:English
Опубликовано: 2008