S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models.

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models.

RATIONALE: Serotonin (5-HT)(2C) receptors are implicated in the control of mood, and their blockade is of potential interest for the management of anxiodepressive states. OBJECTIVES: Herein, we characterized the in vitro and in vivo pharmacological profile of the novel benzourea derivative, S32006....

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Dekeyne, A, Mannoury la Cour, C, Gobert, A, Brocco, M, Lejeune, F, Serres, F, Sharp, T, Daszuta, A, Soumier, A, Papp, M, Rivet, J, Flik, G, Cremers, T, Muller, O, Lavielle, G, Millan, M
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2008

Παρόμοια τεκμήρια

Παρόμοια τεκμήρια