Anti-T-cell reagents for human bone marrow transplantation: ricin linked to three monoclonal antibodies.

Three new reagents that react against human T cells were synthesized by covalently linking the toxin ricin to monoclonal antibodies recognizing differentiation antigens on the surface of T lymphocytes. Each of these immunotoxins selectively inhibited T-cell proliferation when the cells were incubate...

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Dades bibliogràfiques
Autors principals: Vallera, D, Ash, R, Zanjani, E, Kersey, J, LeBien, T, Beverley, P, Neville, D, Youle, R
Format: Journal article
Idioma:English
Publicat: 1983