Disruption of macrodomain protein SCO6735 increases antibiotic production in Streptomyces coelicolor

ADP-ribosylation is a post-translational modification that can alter the physical and chemical properties of target proteins and controls many important cellular processes. Macrodomains are evolutionarily conserved structural domains that bind ADP-ribose derivatives and are found in proteins with di...

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Autors principals: Lalić, J, Posavec Marjanović, M, Palazzo, L, Perina, D, Sabljić, I, Žaja, R, Colby, T, Pleše, B, Halasz, M, Jankevicius, G, Bucca, G, Ahel, M, Matić, I, Ćetković, H, Luić, M, Mikoč, A, Ahel, I
Format: Journal article
Idioma:English
Publicat: American Society for Biochemistry and Molecular Biology 2016