A genetically-targeted ion sensor reveals distinct seizure-related chloride and pH dynamics in GABAergic interneuron populations

Intracellular chloride and pH play fundamental roles in determining a neuron’s synaptic inhibition and excitability. Yet it has been difficult to measure changes in these ions during periods of heightened network activity, such as occur in epilepsy. Here we develop a version of the fluorescent repor...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Călin, A, Waseem, T, Raimondo, JV, Newey, SE, Akerman, CJ
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Cell Press 2023