Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls.
Mitochondria play a central role in the secretion of insulin by pancreatic beta-cells, and pathogenic mutations of mitochondrial DNA (mtDNA) can cause diabetes. The aetiology of type 2 diabetes has a strong genetic component, raising the possibility that genetic variants of mtDNA alter the risk of d...
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Chi tiết về thư mục
| Những tác giả chính: |
Chinnery, P,
Mowbray, C,
Patel, S,
Elson, J,
Sampson, M,
Hitman, G,
McCarthy, M,
Hattersley, A,
Walker, M |
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| Định dạng: | Journal article
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| Ngôn ngữ: | English |
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| Được phát hành: |
2007
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